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Nick Bella

Making Your Building Accessible

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Making your building accessible is no longer just about trying to attract more customers – it is a legal requirement. Even if you have not had to worry about accessibility issues in the past, any changes to the interior of your workplace could well mean that you have to consider using a platform lift to ensure that those with disabilities or reduced mobility can still get around.

This may put off many and serve to make them only look into renovations that allow the building to remain totally accessible without the use of these lifts. However, not only can lifts be far less conspicuous than they once were, but they can actually also simply take the form of stairs and the like too, being easily transformed into a fully functioning lift at the touch of a button.

In short, a disability lift will now no longer necessarily ruin any aesthetic and therefore, when looking to enhance the interior design of your building, it is wise not to let the necessity for accessibility hold you back.

It is not just a platform lift that will be necessary though – from the right size entrances to a layout that will allow wheelchairs to easily move throughout the building, there are many other areas that will have to be taken into consideration when looking to make your building accessible for all.

However, the use of a disability lift or even the addition of regular elevators are not just things that will needlessly cost you money or hold back the designs you create – they are also going to be sure to help you not only get as much custom as possible but also potentially help you find the best staff as well since you will not have to turn away the perfect candidate for a job just because your workplace is not suitable for them.

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The Article is written by ddalifts.co.uk providing disabled lift and wheelchair lift. Visit http://www.ddalifts.co.uk for more information on ddalifts.co.uk Products & Services
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Ready For The Outdoors

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If you are looking for quality outdoor clothing, then you have to choose an excellent array of clothing to meet your needs. Outdoor Clothing  has to be durable, warm, and allow for a great degree of movement. Ideally, you would like you avoid chaffing or bulky clothing that makes walking, hiking or trekking more arduous than it really should be. A high quality parka coat is great for staying warm and their sleek design makes it easy to walk without making things hard going.

Its naturally stylish design looks great, so it is a perfect combination of style and functionality and with a hood and secure inside pockets, you have enough versatility to make your Best Outdoor Clothing experience a success. You can also find a range of accessories that also balance design and functionality from fur-lined hats to softshell gloves to keep you warm. Knitted beanie hats are also a great idea for keeping vital warmth escaping from your head – protection which a hood alone will not give. For hotter environments desert hats protect the neck and shade the sun from the face.

As far as walking boots go, Outdoors Wear  has your feet well protected. A vast selection of different styles of walking boots are available to suit every fashion sense while providing the all important sturdiness and protection you need. From buckle mid boots to sturdy lace-up over ankle boots, you can find styles that are reminiscent of trainers or those that bear more of a resemblance to ski boots. What you are ideally looking for here is a boot that will be waterproof and stand up to whatever the elements can throw at them. By combining abrasion resistant reinforcements, a comfy in-sole, cushioning and grip in all the right places these boots are good to go. The boot should also prevent or minimise the possibility of twisting your foot easily.

Transform a renovation property with wood floors

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Given how property prices have sky rocketed and stayed pretty high even after the credit crunch, it’s hard for first time buyers to find their dream property. But no one has to be priced completely out of the market if they are prepared to take on a renovation job. If a property is structurally sound then putting cosmetic things right isn’t as expensive and daunting as some people think.

Even with a strict budget it’s amazing what can be achieved in a property that needs a little attention. Wood flooring has become incredibly popular in recent years and for good reason. It’s a great way to transform a property. Wood floors manage to be both classic and contemporary at the same time. They suit a period property as well as a more modern apartment. They offer great value for money and will wear well over time.

The choice and prices of wood flooring can vary enormously. There’s something for any property and any budget. For the first time buyer renovating a property it really pays to shop around and the best deals for wood floors are not on the high street. They’re online.

Pro Fit Flooring Direct are one of the UK’s leading suppliers of flooring solutions. They stock a huge range of styles and finishes all at hugely competitive prices. This is the place to come for anyone looking for a great deal and to stretch their budget that little bit further. When it comes to doing up a property every penny counts. By being extremely careful and looking for the best value deals on flooring it’s possible to get the perfect look for that new home. Getting rid of tatty old carpet and putting wood down instead will give any property a whole new look and feel. One that feels instantly more classy and contemporary.

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The Article is written by pro-fitflooringdirect.co.uk providing Wood flooring and wood floors. Visit http://www.pro-fitflooringdirect.co.uk for more information on pro-fitflooringdirect.co.uk Products & Services
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This article is free for reproduction but must be reproduced in its entirety, including live links & this copyright statement must be included. Visit pro-fitflooringdirect.co.uk for more services!

The relevance of modified tubulin antibodies to neuronal research

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A component of chromatin, microtubules (MTs) are rope-like polymers of alpha and beta tubulin, found in practically all eukaryotic cells. Pioneering antibody research showed the tubulin subunits can undergo various post-translational modifications, to regulate MT function. Since then, the discovery of numerous modifying enzymes has enhanced our antibody catalog.

Microtubules are involved in many cellular processes throughout the body. In neurons, MTs play an active part in intracellular organization; axonal elongation; neurite branching; remodeling of dendritic spines; advance of the growth cone and transport of cargo molecules to pre- and post-synaptic domains. These, and many other functions, are regulated in two ways: the integration of alternative tubulin isoforms, and post-translational modifications (PTMs) of a/b-tubulin.

The first PTM to be discovered was acetylation, which until recently was mainly associated with the a-Tubulin Lysine 40 residue, where most MT/protein interactions take place. Others included detyrosination, D2-tubulin generation, glutamylation and glycylation. Early studies described the dynamics, incidence, and potential functions of these modifications. However, it has only been in recent times, with the discovery of tubulin-modifying enzymes, that scientists have been able to probe tubulin at a molecular level.

Neuroscientists now have access to a large antibody catalog to examine the role of tubulin PTMs in neuronal MT regulation, both independently and in combination. A recent hypothesis has suggested that PTM combinations may generate signals to basic and higher neuronal functions to create a readable MT code, similar to the histone code. Antibodies to downstream effectors would probably target proteins with roles in intracellular transport, neuronal differentiation and polarization.

Recent antibody studies have clarified the role that three key tubulin modifications play in regulating kinesin motor proteins and their cargoes along specific MT tracks. It is suggested all modifications share a common role within the cell, targeting motor proteins and MT-associated proteins (MAPs) to defined microtubule subsets. As one of the world’s leading antibody suppliers, we at Novus Biologicals have an extensive antibody database of tubulin research products.

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The Article is written by novusbio.com providing antibody catalogue and antibody database Services. Visit http://www.novusbio.com for more information on novusbio.com Products & Services
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This article is free for reproduction but must be reproduced in its entirety, including live links & this copyright statement must be included. Visit novusbio.com for more services!

The importance of an accurate valuation

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When selling or letting a home, it is essential that an accurate valuation is received. This helps determine what the price should be, and attract a high number of viewings. However, a wrong valuation could result in a property not selling or letting, or going for too low a price.

Determining the valuation is not as straightforward as many initially think. It can be a difficult and protracted process. Further than this, it is interesting to note that even some of the best estate agents and letting agents do not actually conduct detailed home valuations.

Instead, the value they give is more an indication as to the most appropriate price, related to the current market conditions in the area at the time. There are those who will also use experienced valuers, working to the Royal Institution of Chartered Surveyors (RICS) code, which follows a set series of criteria.

The code defines that a property should be valued according to its type, age, number of bedrooms and any fixtures and fittings included in the sale. This all seem fairly straight forward then, but does go further than this.

The RICS code also rates the value of a property against its position in the local area, its access to local amenities, as well as its construction and the state of repair it is in. The final consideration is against the tenure, ongoing tenancies, service charges and any other liabilities.

Before seeking valuations from local estate agents, it is well worth asking them what exactly they are able to provide. On the back of this information, it may be necessary to seek a more detailed appraisal independently.

The importance of an accurate valuation goes hand in hand with having a competent agent working on the property owner’s behalf. To this end, Meet My Agent provide a forum for sellers and landlords to leave their own lettings and estate agent reviews, helping others choose the best to work with.

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The Article is written by meetmyagent.co.uk providing best estate agents and estate agent reviews Services. Visit http://www.meetmyagent.co.uk for more information on meetmyagent.co.uk Products & Services
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This article is free for reproduction but must be reproduced in its entirety, including live links & this copyright statement must be included. Visit meetmyagent.co.uk for more services!